Regulating the regulator: MicF RNA controls expression of the global regulator Lrp
نویسندگان
چکیده
منابع مشابه
KynR, a Lrp/AsnC-type transcriptional regulator, directly controls the kynurenine pathway in Pseudomonas aeruginosa.
The opportunistic pathogen Pseudomonas aeruginosa can utilize a variety of carbon sources and produces many secondary metabolites to help survive harsh environments. P. aeruginosa is part of a small group of bacteria that use the kynurenine pathway to catabolize tryptophan. Through the kynurenine pathway, tryptophan is broken down into anthranilate, which is further degraded into tricarboxylic ...
متن کاملThe Global Response Regulator RegR Controls Expression of Denitrification Genes in Bradyrhizobium japonicum
Bradyrhizobium japonicum RegSR regulatory proteins belong to the family of two-component regulatory systems, and orthologs are present in many Proteobacteria where they globally control gene expression mostly in a redox-responsive manner. In this work, we have performed a transcriptional profiling of wild-type and regR mutant cells grown under anoxic denitrifying conditions. The comparative ana...
متن کاملThe cardiac 26S proteasome: regulating the regulator.
Significance of Ubiquitin–Proteasome– Mediated Degradation of Proteins The ubiquitin–proteasome system (UPS) is the main pathway for the nonlysosomal degradation of intracellular proteins, representing upwards of 80% of all intracellular proteins. A key component of the UPS is the 26S proteasome, a macromolecular multisubunit complex that has the responsibility of recognizing, unfolding, and th...
متن کاملCK2 and PML: Regulating the Regulator
The PML protein induces senescence, and, upon oncogenic stress, its absence promotes cellular transformation. In this issue of Cell, Scaglioni et al. (2006) show that phosphorylation of PML by CK2, a kinase frequently activated in human cancers, promotes PML degradation. Therefore, pharmacological inhibition of CK2-induced PML loss could be used to offset tumor establishment.
متن کاملThe effect of resistance training on the expression of cardiac muscle growth regulator messenger genes in obese male rats
Background: Obesity is associated with cardiovascular disease, followed by pathological cardiac hypertrophy. However, physical activity (resistance training) plays a role in modulating some of the intracellular messenger pathways associated with the regulation of pathologic hypertrophy. The aim of this study was to investigate The effect of resistance training on the expression of cardiac muscl...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular Microbiology
سال: 2012
ISSN: 0950-382X
DOI: 10.1111/j.1365-2958.2012.08030.x